Wnt Pathways


The Wnt signaling pathway regulates the developmental processes of cell fate and plays a role in tumorigenesis and progression. Wnt signaling comprises three pathways: the canonical pathway and two non-canonical pathways, planar cell polarity (PCP) and a calcium ion-dependent pathway. The canonical pathway is dependent on beta-catenin and regulates the cell cycle, cell growth, and proliferation. This panel includes the Wnt signaling ligands and receptors as well as other auxiliary signaling molecules for regulation, proteolysis, cell migration, cell cycle, adhesion, and EMT/metastasis.

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