Genes Included
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ADAM8ADRB2AKT1AKT1S1AKT2ALKANGPTL4APCATF1BADBCL2BDNFBIRC3BMP2BRAFBRCA1BRCA2CAB39LCASP3CASP9CC2D1BCCNB1CCND1CCND2CD274CDH1CDH2CDK1CDK2CDK4CDKN1ACDKN1BCOG7COL2A1CTNNB1CXCL1CXCL2CXCR4DDIT3DUSP1DUSP4DUSP5DUSP6E2F1EDC3EGFEGFREGR1EIF2AEIF4EBP1EIF4G1EPHA2ERBB2ERBB3EREGESR1FASFASLGFBXW7FGF2FGF6FGF9FGF16FGF17FGF22FGFR2FGFR3FN1FOSFOXO1GADD45AGADD45GGDNFGNA11GNAQGNGT1GPATCH3GRB2GRK2GSK3AGSK3BHBEGFHDAC3HGFHRASHSP90B1IGF1RIGFBP1IKBKBIL1AIL2RGIL7RIL8IRS1ITGA2ITGA6ITGB2JAK2JUNKEAP1KITKLF5KRASLAMA3LCKLDLRMAP2K1MAP2K2MAP2K6MAP3K1MAPK1MAPK8MAPK9MAPK10MAPKAP1METMKI67MMP14MTMR14MTORMYBMYCMYCNMYD88NEDD4NF1NFE2L2NGFNOS3NRASNUBP1PCNAPDGFAPDK1PGRPHLDA1PIK3CAPIK3CDPIK3R3PIM1PLAURPRKAA2PRKCBPRPF38APTENPTPN11PTPRRPVRRAC1RAF1RASGRP1ROS1RPS6RPS6KA1RPS6KB1RPTORSAP130SERPINB2SF3A3SFNSLC2A1SLC9A1SMAD2SNAI1SNAI2SNAI3SOD2SPP1SPRY4SQSTM1STK11TBK1TCF3TFPI2TGFB1TGFB2THEM4TLK2TLR4TNFTNFRSF10BTP53TRAF2TRIB3TSC1TSC2TWIST1VEGFAZC3H14ZEB1ZEB2ZFP36
SKU: mapk-pi3k-pathways-human.
Category: Human.
Genes: ADAM8.ADRB2.AKT1.AKT1S1.AKT2.ALK.ANGPTL4.APC.ATF1.BAD.BCL2.BDNF.BIRC3.BMP2.BRAF.BRCA1.BRCA2.CAB39L.CASP3.CASP9.CC2D1B.CCNB1.CCND1.CCND2.CD274.CDH1.CDH2.CDK1.CDK2.CDK4.CDKN1A.CDKN1B.COG7.COL2A1.CTNNB1.CXCL1.CXCL2.CXCR4.DDIT3.DUSP1.DUSP4.DUSP5.DUSP6.E2F1.EDC3.EGF.EGFR.EGR1.EIF2A.EIF4EBP1.EIF4G1.EPHA2.ERBB2.ERBB3.EREG.ESR1.FAS.FASLG.FBXW7.FGF16.FGF17.FGF2.FGF22.FGF6.FGF9.FGFR2.FGFR3.FN1.FOS.FOXO1.GADD45A.GADD45G.GDNF.GNA11.GNAQ.GNGT1.GPATCH3.GRB2.GRK2.GSK3A.GSK3B.HBEGF.HDAC3.HGF.HRAS.HSP90B1.IGF1R.IGFBP1.IKBKB.IL1A.IL2RG.IL7R.IL8.IRS1.ITGA2.ITGA6.ITGB2.JAK2.JUN.KEAP1.KIT.KLF5.KRAS.LAMA3.LCK.LDLR.MAP2K1.MAP2K2.MAP2K6.MAP3K1.MAPK1.MAPK10.MAPK8.MAPK9.MAPKAP1.MET.MKI67.MMP14.MTMR14.MTOR.MYB.MYC.MYCN.MYD88.NEDD4.NF1.NFE2L2.NGF.NOS3.NRAS.NUBP1.PCNA.PDGFA.PDK1.PGR.PHLDA1.PIK3CA.PIK3CD.PIK3R3.PIM1.PLAUR.PRKAA2.PRKCB.PRPF38A.PTEN.PTPN11.PTPRR.PVR.RAC1.RAF1.RASGRP1.ROS1.RPS6.RPS6KA1.RPS6KB1.RPTOR.SAP130.SERPINB2.SF3A3.SFN.SLC2A1.SLC9A1.SMAD2.SNAI1.SNAI2.SNAI3.SOD2.SPP1.SPRY4.SQSTM1.STK11.TBK1.TCF3.TFPI2.TGFB1.TGFB2.THEM4.TLK2.TLR4.TNF.TNFRSF10B.TP53.TRAF2.TRIB3.TSC1.TSC2.TWIST1.VEGFA.ZC3H14.ZEB1.ZEB2.ZFP36
Aliases: 4E-BP1.A170.ACH.ACS3.ADRB2R.ADRBK1.ADRBR.AFBP.AGO.AKT.AMPK.AMPKa2.AOM.AP-1.APAF-3.API2.APNH.APO-1.apopain.APT1.APT1LG1.AREB6.armadillo.ARMD10.ARP4.AT225.ATF1.ATF2.B2AR.B7-H.B7-H1.B7H1.bA103J18.3.BAR.BARK1.BBC2.Bcl-2.BCL1.BCL2L8.BEK.beta-catenin.bHLHa38.bHLHb21.bHLHe37.bHLHe39.BM600-150kDa.BMP2A.BNSP.BPES2.BPES3.BPTP3.BRAF1.BRCC1.BRCC2.BSPI.BTEB2.BZP.BZS.c-fos.c-IAP2.c-Jun.C-Kit.c-myb.c-Myc.c-Raf.c-ros-1.C20orf97.C3orf29.CalDAG-GEFII.CAP20.CCNB.CD117.CD127.CD132.CD155.CD156.CD156a.CD178.CD18.CD184.CD221.CD246.CD262.CD284.CD324.CD325.CD332.CD333.CD340.CD49B.CD49f.CD87.CD95.CDC2.CDC28A.CDC4.CDHN.CDKN1.CED.CEK2.CEK3.CFD1.CHOP.CHOP10.cIAP2.CIDX.CIG.CINC-2a.CIP1.CKLF.CL100.CPP32.CPP32B.CR6.CRAF.CRS.CRS1.CSE.CTMP.CTNNB.CXCL8.D11S287E.D2S201E.DDIT1.DDIT2.DFNB39.DFNB97.DIF.dJ1103G7.3.DP2.DP2.5.DP3.DPD1.DR5.DT1P1B11.DTR.DTS.DYT18.DYT9.E2A.E47.EC-PTP.ECK.ECNOS.ECT1.EIF-2A.EIF4F.EIF4G.eNOS.epiligrin.ER.Era.ERBB.ERBB1.ERK.ERK2.ESR.ETA-1.F-TCF.FACD.FAD.FAD1.FANCD.FANCD1.FANCS.FAS1.FasL.FBH.FBH2.FBW7.FBX30.FBXW6.FECD6.FGF-13.FGFB.FHH2.FIAF.FINC.FKH1.FKHR.FLJ11071.FLJ11806.FLJ12455.FLJ12577.FLJ12761.FLJ14936.FLJ21128.FLJ22405.FLJ44809.FLJ90311.FOXO1A.FRAP.FRAP1.FRAP2.FSP.fusin.G-ALPHA-q.G0S24.G0S30.GADD153.GADD45.GADD45gamma.GAQ.GCP-1.GFND2.GLUT.GLUT1.GNG1.GP96.GPATC3.GRO1.GRO2.GROa.GROb.GRP17.GRP94.H-twist.hamartin.HD3.hEDTP.HEGFL.HER-2.HER2.HER3.HFARP.HFB1-GDNF.HGFB.HGFR.HHC2.hiap-1.hIGFBP-1.HIRS-1.hJumpy.HM89.HPTA.HRAS1.HsT1201.HSY3RR.HTLVR.hToll.HU-1.HVED.HVH1.HVH2.HVH3.hYjeF_N2-15q23.IBP1.ICE-LAP6.IGF-BP25.IGFIR.IGFR.IKK-beta.IKK2.IKKB.IKLF.IL-1A.IL1.IL1-ALPHA.IL1F1.IMD4.INrf2.ITF1.JNK.JNK1.JNK2.JNK3.JTK10.JTK13.JTK4.JV18-1.JWS.K-SAM.kalinin-165kDa.KGFR.KIAA0093.KIAA0132.KIAA0243.KIAA0569.KIAA1303.KIAA1836.KILLER.KIP1.KLHL19.KOG1.KRAS1.KRAS2.KROX-24.LAM.LAMNA.LCCS2.LDLCQ2.LESTR.LETS.LFA-1.LFS1.LKB1.Lobe.LSM16.MAC-1.MADH2.MADR2.MALT2.MAPK2.MAPKK1.MAPKK6.MAPKKK1.MCF3.MCH6.MEK1.MEK2.MEK6.MEKK.MEKK1.MF4.MFI7.MGC10630.MGC1114.MGC129647.MGC129648.MGC176705.MGC18216.MGC20887.MGC2745.MGC2865.MGC4407.MGC44450.MGC9454.MGSA.MGSA-a.MGSA-b.MHAM.MIB-.MIHC.MIP-2a.MIP1.MKK6.MKP-1.MKP-2.MKP-3.MMAC1.MO2L.MS2.MSF.MT1-MMP.MYCC.MYCNOT.N-myc.N-ras.NAK.NAP-3.NBP1.NBP35.NCAD.NCKAP2.Necl-5.NECL5.NEDD4-1.NEU.NFKBIKB.NGFB.NGFI-A.NGL.NHE1.nicein-150kDa.NIL-2-A.NL2.NMYC.NPY3R.NPYR.NPYY3R.NR3A1.NR3C3.NRF2.NS1.NUP475.NY-REN-37.OPN.OSIL.p110D.P21.p21-Rac1.p21CIP1.p21Cip1/Waf1.p220.P27KIP1.p41mapk.p493F12.p53.p54a.p54bSAPK.p55.p60.p62.p62B.p70(S6K)-alpha.p90Rsk.PAI2.PARK18.PBT.PCPTP1.PD-L1.PDB3.PDCD1LG1.PDGF-A.PDGF1.PDL1.PGAR.PHAS-I.PHRIP.PI3K.PIM.PJS.PKB.PKCB.PKU-ALPHA.PLANH2.pp1158.PP12.PP5.PPCD3.PPP1R105.PPP1R143.PPP1R160.PPP1R46.PPP1R50.PPP1R53.PPP1R56.PR.PRAD1.PRAS40.PRKAA.PRKBA.PRKCB1.PRKCB2.PRKM1.PRKM10.PRKM2.PRKM8.PRKM9.PRKMK1.PRKMK2.PRKMK6.Prp38.PRP9.PRPF9.PS6K.PSK-J3.PTEN1.PTP-SL.PTP2C.PTPBR7.PTPN10.PTPRQ.PVS.PYST1.RAC.Rac-1.Raf-1.RAFT1.RAPT1.raptor.RASGRP.RBBP3.RBP3.RCCP2.REF1.RNF162A.RNF49.RNF53.ROS.RPD3.RPD3-2.RPF1.RSK.RSK1.S6.S6K1.SAP61.SAPK.SAPK1.SAPKK3.SCFR.SCIDX1.SCS.SCYB1.SCYB2.SDI1.SEDC.SEL-10.SEL10.SF.SF3a60.SH-PTP2.SHP-2.SHP2.SIN1.SIP-1.SIP1.SLUG.SLUGH1.SLUGH2.SMUC.SNA.SNAH.SNAIL.SNAIL1.SNAIL2.STK14A.STL1.Tage4.TC-25.TCF8.TDAG51.TEP1.TFPI-2.TGFB.TGFbeta.TIS11.TIS8.TK14.TK25.TLR-4.TNF-alpha.TNFA.TNFRSF6.TNFSF2.TNFSF6.TRA1.TRAIL-R2.TRAP3.TRB3.TREB36.TRICK2A.TRICKB.TSC.TSC4.TTP.tuberin.TWIST.TYP.U21B31.UKp68.UPAR.URKR.UVO.uvomorulin.VDIR.VEGF.VEGF-A.VPF.WAF1.XRCC11.Yama.YJDC.YJEFN2.YWHAS.ZEB.Zfhep.Zfhx1a.ZFHX1B.Zfp293.ZIF-268.ZNF225.ZNF293
Genes: ADAM8.ADRB2.AKT1.AKT1S1.AKT2.ALK.ANGPTL4.APC.ATF1.BAD.BCL2.BDNF.BIRC3.BMP2.BRAF.BRCA1.BRCA2.CAB39L.CASP3.CASP9.CC2D1B.CCNB1.CCND1.CCND2.CD274.CDH1.CDH2.CDK1.CDK2.CDK4.CDKN1A.CDKN1B.COG7.COL2A1.CTNNB1.CXCL1.CXCL2.CXCR4.DDIT3.DUSP1.DUSP4.DUSP5.DUSP6.E2F1.EDC3.EGF.EGFR.EGR1.EIF2A.EIF4EBP1.EIF4G1.EPHA2.ERBB2.ERBB3.EREG.ESR1.FAS.FASLG.FBXW7.FGF16.FGF17.FGF2.FGF22.FGF6.FGF9.FGFR2.FGFR3.FN1.FOS.FOXO1.GADD45A.GADD45G.GDNF.GNA11.GNAQ.GNGT1.GPATCH3.GRB2.GRK2.GSK3A.GSK3B.HBEGF.HDAC3.HGF.HRAS.HSP90B1.IGF1R.IGFBP1.IKBKB.IL1A.IL2RG.IL7R.IL8.IRS1.ITGA2.ITGA6.ITGB2.JAK2.JUN.KEAP1.KIT.KLF5.KRAS.LAMA3.LCK.LDLR.MAP2K1.MAP2K2.MAP2K6.MAP3K1.MAPK1.MAPK10.MAPK8.MAPK9.MAPKAP1.MET.MKI67.MMP14.MTMR14.MTOR.MYB.MYC.MYCN.MYD88.NEDD4.NF1.NFE2L2.NGF.NOS3.NRAS.NUBP1.PCNA.PDGFA.PDK1.PGR.PHLDA1.PIK3CA.PIK3CD.PIK3R3.PIM1.PLAUR.PRKAA2.PRKCB.PRPF38A.PTEN.PTPN11.PTPRR.PVR.RAC1.RAF1.RASGRP1.ROS1.RPS6.RPS6KA1.RPS6KB1.RPTOR.SAP130.SERPINB2.SF3A3.SFN.SLC2A1.SLC9A1.SMAD2.SNAI1.SNAI2.SNAI3.SOD2.SPP1.SPRY4.SQSTM1.STK11.TBK1.TCF3.TFPI2.TGFB1.TGFB2.THEM4.TLK2.TLR4.TNF.TNFRSF10B.TP53.TRAF2.TRIB3.TSC1.TSC2.TWIST1.VEGFA.ZC3H14.ZEB1.ZEB2.ZFP36
Aliases: 4E-BP1.A170.ACH.ACS3.ADRB2R.ADRBK1.ADRBR.AFBP.AGO.AKT.AMPK.AMPKa2.AOM.AP-1.APAF-3.API2.APNH.APO-1.apopain.APT1.APT1LG1.AREB6.armadillo.ARMD10.ARP4.AT225.ATF1.ATF2.B2AR.B7-H.B7-H1.B7H1.bA103J18.3.BAR.BARK1.BBC2.Bcl-2.BCL1.BCL2L8.BEK.beta-catenin.bHLHa38.bHLHb21.bHLHe37.bHLHe39.BM600-150kDa.BMP2A.BNSP.BPES2.BPES3.BPTP3.BRAF1.BRCC1.BRCC2.BSPI.BTEB2.BZP.BZS.c-fos.c-IAP2.c-Jun.C-Kit.c-myb.c-Myc.c-Raf.c-ros-1.C20orf97.C3orf29.CalDAG-GEFII.CAP20.CCNB.CD117.CD127.CD132.CD155.CD156.CD156a.CD178.CD18.CD184.CD221.CD246.CD262.CD284.CD324.CD325.CD332.CD333.CD340.CD49B.CD49f.CD87.CD95.CDC2.CDC28A.CDC4.CDHN.CDKN1.CED.CEK2.CEK3.CFD1.CHOP.CHOP10.cIAP2.CIDX.CIG.CINC-2a.CIP1.CKLF.CL100.CPP32.CPP32B.CR6.CRAF.CRS.CRS1.CSE.CTMP.CTNNB.CXCL8.D11S287E.D2S201E.DDIT1.DDIT2.DFNB39.DFNB97.DIF.dJ1103G7.3.DP2.DP2.5.DP3.DPD1.DR5.DT1P1B11.DTR.DTS.DYT18.DYT9.E2A.E47.EC-PTP.ECK.ECNOS.ECT1.EIF-2A.EIF4F.EIF4G.eNOS.epiligrin.ER.Era.ERBB.ERBB1.ERK.ERK2.ESR.ETA-1.F-TCF.FACD.FAD.FAD1.FANCD.FANCD1.FANCS.FAS1.FasL.FBH.FBH2.FBW7.FBX30.FBXW6.FECD6.FGF-13.FGFB.FHH2.FIAF.FINC.FKH1.FKHR.FLJ11071.FLJ11806.FLJ12455.FLJ12577.FLJ12761.FLJ14936.FLJ21128.FLJ22405.FLJ44809.FLJ90311.FOXO1A.FRAP.FRAP1.FRAP2.FSP.fusin.G-ALPHA-q.G0S24.G0S30.GADD153.GADD45.GADD45gamma.GAQ.GCP-1.GFND2.GLUT.GLUT1.GNG1.GP96.GPATC3.GRO1.GRO2.GROa.GROb.GRP17.GRP94.H-twist.hamartin.HD3.hEDTP.HEGFL.HER-2.HER2.HER3.HFARP.HFB1-GDNF.HGFB.HGFR.HHC2.hiap-1.hIGFBP-1.HIRS-1.hJumpy.HM89.HPTA.HRAS1.HsT1201.HSY3RR.HTLVR.hToll.HU-1.HVED.HVH1.HVH2.HVH3.hYjeF_N2-15q23.IBP1.ICE-LAP6.IGF-BP25.IGFIR.IGFR.IKK-beta.IKK2.IKKB.IKLF.IL-1A.IL1.IL1-ALPHA.IL1F1.IMD4.INrf2.ITF1.JNK.JNK1.JNK2.JNK3.JTK10.JTK13.JTK4.JV18-1.JWS.K-SAM.kalinin-165kDa.KGFR.KIAA0093.KIAA0132.KIAA0243.KIAA0569.KIAA1303.KIAA1836.KILLER.KIP1.KLHL19.KOG1.KRAS1.KRAS2.KROX-24.LAM.LAMNA.LCCS2.LDLCQ2.LESTR.LETS.LFA-1.LFS1.LKB1.Lobe.LSM16.MAC-1.MADH2.MADR2.MALT2.MAPK2.MAPKK1.MAPKK6.MAPKKK1.MCF3.MCH6.MEK1.MEK2.MEK6.MEKK.MEKK1.MF4.MFI7.MGC10630.MGC1114.MGC129647.MGC129648.MGC176705.MGC18216.MGC20887.MGC2745.MGC2865.MGC4407.MGC44450.MGC9454.MGSA.MGSA-a.MGSA-b.MHAM.MIB-.MIHC.MIP-2a.MIP1.MKK6.MKP-1.MKP-2.MKP-3.MMAC1.MO2L.MS2.MSF.MT1-MMP.MYCC.MYCNOT.N-myc.N-ras.NAK.NAP-3.NBP1.NBP35.NCAD.NCKAP2.Necl-5.NECL5.NEDD4-1.NEU.NFKBIKB.NGFB.NGFI-A.NGL.NHE1.nicein-150kDa.NIL-2-A.NL2.NMYC.NPY3R.NPYR.NPYY3R.NR3A1.NR3C3.NRF2.NS1.NUP475.NY-REN-37.OPN.OSIL.p110D.P21.p21-Rac1.p21CIP1.p21Cip1/Waf1.p220.P27KIP1.p41mapk.p493F12.p53.p54a.p54bSAPK.p55.p60.p62.p62B.p70(S6K)-alpha.p90Rsk.PAI2.PARK18.PBT.PCPTP1.PD-L1.PDB3.PDCD1LG1.PDGF-A.PDGF1.PDL1.PGAR.PHAS-I.PHRIP.PI3K.PIM.PJS.PKB.PKCB.PKU-ALPHA.PLANH2.pp1158.PP12.PP5.PPCD3.PPP1R105.PPP1R143.PPP1R160.PPP1R46.PPP1R50.PPP1R53.PPP1R56.PR.PRAD1.PRAS40.PRKAA.PRKBA.PRKCB1.PRKCB2.PRKM1.PRKM10.PRKM2.PRKM8.PRKM9.PRKMK1.PRKMK2.PRKMK6.Prp38.PRP9.PRPF9.PS6K.PSK-J3.PTEN1.PTP-SL.PTP2C.PTPBR7.PTPN10.PTPRQ.PVS.PYST1.RAC.Rac-1.Raf-1.RAFT1.RAPT1.raptor.RASGRP.RBBP3.RBP3.RCCP2.REF1.RNF162A.RNF49.RNF53.ROS.RPD3.RPD3-2.RPF1.RSK.RSK1.S6.S6K1.SAP61.SAPK.SAPK1.SAPKK3.SCFR.SCIDX1.SCS.SCYB1.SCYB2.SDI1.SEDC.SEL-10.SEL10.SF.SF3a60.SH-PTP2.SHP-2.SHP2.SIN1.SIP-1.SIP1.SLUG.SLUGH1.SLUGH2.SMUC.SNA.SNAH.SNAIL.SNAIL1.SNAIL2.STK14A.STL1.Tage4.TC-25.TCF8.TDAG51.TEP1.TFPI-2.TGFB.TGFbeta.TIS11.TIS8.TK14.TK25.TLR-4.TNF-alpha.TNFA.TNFRSF6.TNFSF2.TNFSF6.TRA1.TRAIL-R2.TRAP3.TRB3.TREB36.TRICK2A.TRICKB.TSC.TSC4.TTP.tuberin.TWIST.TYP.U21B31.UKp68.UPAR.URKR.UVO.uvomorulin.VDIR.VEGF.VEGF-A.VPF.WAF1.XRCC11.Yama.YJDC.YJEFN2.YWHAS.ZEB.Zfhep.Zfhx1a.ZFHX1B.Zfp293.ZIF-268.ZNF225.ZNF293
