A growing number of protein therapies are becoming more and more available for patient use, resulting in the need for controlled and consistent manufacturing. Because of the strict product quality and safety requirements, downstream purification of biologics is costly, often creating a major bioprocessing bottleneck (Lightfoot et al. 2004). As a result, it is critical to choose a host cell protein detection (HCP) kit that can detect an extensive range of host cell protein (high coverage) to prevent an adverse immune response. It is also important that the CHO HCP ELISA kits exhibit negligible lot-to lot variability to reduce cost due to conflicting results in the bioprocess. Canopy’s CHO HCP ELISA Kit was engineered by a bioprocessing scientist to specifically address problems with inconsistencies of current CHO HCP ELISA kits and to ultimately reduce cost in biomanufacturing.

References

Lightfoot EN, Moscariello JS. Bioseparations. Biotechnol Bioeng.
2004;87:259–273.

Canopy HCP CHO Datasheet

Please click on the link below to open a PDF discussing the competitive advantage of our CHO HCP ELISA Kit.
Canopy’s CHO HCP ELISA Kit vs Leading Competitor

CHO HCP ELISA Kits

HCP001 - CHO Host Cell Protein ELISA Kit
This is a complete kit for determining host cell protein contamination in products expressed in CHO.
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HCP006 - CHO Host Cell Protein Standards
Used as internal control for the Western blot analysis of CHO host cell proteins or development of HCP ELISA. Supplied at 0.5 mg/ml and available as 50 µl (25 µg) and 200 µl (100 µg) sizes.
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HCP008 - Biotin-labeled Anti-human IgG antibody
Used in conjunction with anti-CHO HCP antibodies to identify which bands are HCPs and which bands are IgG-derived. Supplied at 1 mg/ml.
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HCP009 - CHO Host Cell Protein Antibody for Western Blot Analysis
Western blot detection and characterization of CHO host cell proteins. Supplied as purified IgG at 1 mg/ml.
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HCP010 - Biotin-labeled anti-CHO Host Cell Protein Antibody for Western Blot Analysis
Western blot detection and characterization of CHO host cell proteins. Supplied at 1 mg/ml.
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