Canopy
Zellkraftwerk

PanCancer Pathways Panel

Human and Mouse

The PanCancer Pathways Panel allows you to conduct multiplex gene expression analysis with 770 genes from 13 cancer-associated canonical pathways including: MAPK, STAT, PI3K, RAS, Cell cycle, Apoptosis, Hedgehog, Wnt, DNA damage control, Transcriptional regulation, Chromatin modification, and TGF-β

Benefits

01

Highly multiplexed analysis of basic cancer biology and pathway deregulation activity.

02

Measure treatment effects on pathways and examine cancer escape mechanisms.

03

Rapidly and easily screen samples for biomarker discovery or drug mechanism of action studies.

04

Part of the PanCancer panel collection, embracing the Hallmarks of Cancer and aimed at understanding the complexities of cancer.

Details & data

PanCancer Pathways: Understanding basic cancer biology and pathway deregulation

  • Score pathway deregulation with end-to-end analysis
  • Generate follow-up research hypothesis using pathway visualizations
  • Measure gene expression with 770 genes representing all major cancer pathways including: Wnt, Hedgehog, apoptosis, cell cycle, RAS, PI3K, STAT, MAPK, Notch, TGF-β, chromatin modification, transcriptional regulation, and DNA damage control

 

PanCancer Pathways Pathways and Processes
Category/PathwayHuman genes
Mouse genes
Representative Hallmarks
Cancer driver genes
124125-
Cell cycle and apoptosis
137134Resisting cell death
Chromatin modification
2223Genome instability and mutation
DNA repair
5070Genome instability and mutation
Hedgehog pathway
2831Resisting cell death
JAK-STAT pathway
86
96Sustaining proliferative signaling
MAPK pathway
157159Sustaining proliferative signaling
Notch pathway
2427Enabling replicative immortality
PI3K pathway
201209Deregulating cellular energetics
RAS pathway
142147Sustaining proliferative signaling
TGF-β pathway
5153Evading growth suppressors
Transcriptional misregulation
101103Genome instability and mutation
Wnt pathway
7884Enabling replicative immortality

Genes in panel

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