Autoimmune Discovery

Human

This 770 gene panel is designed to enable researchers to discover links between known autoimmune disease associated germline variants and their gene expression. The genes in this panel were selected from the top nine autoimmune diseases, providing an ideal tool to explore disease-associated mutation gene functionality and biomarker characterization. The comprehensive content enables gene expression profiling of immune response together with the gene mutations. Together, these traits allow researchers to identify new gene functions and look at gene expression in response to treatment.

Benefits

01

Investigate the relationship between gene variant expression patterns and immune response.

02

Identify novel therapeutic targets and biomarkers.

03

Understand the function of disease associated genes and germ line variants.

Details & data

Genes were selected and annotated for evidence of association in 9 autoimmune disorders and human immune response. The genes considered for inclusion were based on both data driven and biological selection methods. The table below outlines the 9 autoimmune diseases focused on and the panel content associated.

Disease Association
Description
# Genes
Multiple SclerosisDemyelinating disease of the nervous system104
Rheumatoid ArthritisChronic inflammatory disorder of joints95
Systemic Lupus ErythematosusInflammation and damage to various body tissues55
Type 1 DiabetesDisease that causes damage to beta cells in the pancreas44
Ankylosing SpondylitisChronic inflammatory disorder of the spine43
Celiac DiseaseImmune response to gluten that damages small intestine249
Ulcerative ColitisDisease causing inflammation and ulcers in large intestine200
Inflammatory Bowel DiseaseInflammation of the digestive tract249
PsoriasisDeficiency in function of multiple endocrine glands48
Other Immune ResponseHuman immune response genes237

Genes in panel

Pricing

Autoimmune Discovery

$5,300.00

$
Step 3

Price

Number of samples
$5,300.00*
*price includes reagents
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