V-PLEX Th17 Panel 1 Human Kit

Human

The V-PLEX Th17 Panel 1 (human) is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Th17 Panel 1 (human) includes seven key Th17 pathway markers that are important in inflammation response and immune system regulation as well as numerous other biological processes. The kit enables the sensitive detection of native and recombinant human IL-17A (assay generation B), IL-21, IL-22, IL-23, IL-27, IL-31, and MIP-3α in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs.

T cells of the Th17 lineage mediate host defense mechanisms to various infections and play a crucial role in crosstalk between the immune system and affected tissue. Th17 cells are a critical part of the immune system and act as a bridge between the innate and adaptive immune systems. Improper regulation of their proinflammatory activities contributes to numerous pathogenic conditions. They are important biomarkers for inclusion in researchers’ repertoire of cytokine and proinflammatory assays. The utility of these biomarkers can be enhanced through multiplexing which reduces assay times and sample volumes.

Dynamic range: 

  • IL-17A: 5.86–1950 pg/mL
  • IL-21: 1.65-650 pg/mL
  • IL-22: 2.78-325 pg/mL
  • IL-23: 4.60-3258 pg/mL
  • IL-27: 38.7-13,000 pg/mL
  • IL-31: 4.22-650 pg/mL
  • MIP-3α: 0.588-325 pg/mL

Biomarkers in panel

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V-PLEX Th17 Panel 1 Human Kit

$4,490.00

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$4,490.00
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