Exposure to specific agents (such as reactive oxygen species, methylating agents, etc.) and even normal physiological processes all damage DNA. Cells must repair DNA damage to prevent mutations from propagating into cancer and accumulating. This panel includes the genes involved in major DNA damage repair pathways including base excision repair, nucleotide excision repair, mismatch repair, translesion synthesis, and other repair processes. Additional genes from apoptosis and cell cycle pathways are included.