Full speed. Half speed. Full stop. Those are the usual choices for controlling the amount of protein produced from a particular gene. Other speeds are possible, but they typically require a lot of effort on the part of scientists, who often resort to the identification and exploitation of a hypomorphic mutation, that is, a mutation that causes a partial loss of gene function. Hypomorphic mutations, however, are usually hard to come by. They may be limited to a specific organism, change gene expression unpredictably, or depend on changes in the spatial–temporal expression of the targeted gene.
Read GEN’s article Sergej Djuranovic’s recent publication in Nature Communications. The work in the publication is the basis of our TUNR technology.
Read the GEN article
Read the Nature Communications article